杰森·伯恩事件引起连锁反应，踏脚石（Treadstone）计划以及CIA用药物控制强化特工的行径通过报纸公之于众，令其幕后人物坐立不安。为了阻止满盘皆输的局面出现，CIA高层决定中止该计划，并将相关特工人员以及科学家从行动中抹杀。在此后的日子里，那些深藏在国家政治最底层、依靠蓝绿药丸执行各种绝密任务的特工相继殒命，而负责染脏双手的执行人——前美国空军上校艾瑞克·贝尔（爱德华·诺顿 Edward Norton 饰），正慢慢将屠刀伸向隐藏在位于阿拉斯加崇山峻岭、暴雪深山中的特工艾伦·克劳斯（杰瑞米·雷纳 Jeremy Renner 饰）。 　　突如其来的炮火袭击令艾伦意识到自己所处的危险境地，在之后的日子里，他不仅要在昔日同伴的追杀中求生，还必须设法找到那曾为他提供源源不断体能和智力的蓝绿药丸……

本片是《沉默的羔羊》十周年纪念日推出的续集，这一集故事仍然改编自作家托马斯哈里斯的小说。

Inspired by the original hit Swedish novel and film,the series centers on Mark and his daughter Eleanor, whose lives were changed 10 years earlier when she was turned into a vampire. Starring Demián Bichir, Anika Noni Rose, Grace Gummer, Madison Taylor Baez, Kevin Carroll, Ian Foreman and Jacob Buster. Stream the premiere October 7. 　　Inspired by the original hit Swedish novel and film,the series centers on Mark (Bichir) and his daughter Eleanor (Baez), whose lives were changed 10 years earlier when she was turned into a vampire. Locked in at age 12, perhaps forever, Eleanor lives a closed-in life, able to go out only at night, while her father does his best to provide her with the human blood she needs to stay alive. With these emotionally charged and terrifying ingredients as a starting point,LET THE RIGHT ONE INwill upend genre expectations, turning a naturalistic lens on human frailty, strength and compassion. Led by Oscar nominee Demián Bichir (A Better Life), the series also stars Tony winner Anika Noni Rose (Dreamgirls, Power), Grace Gummer (Mr. Robot), Madison Taylor Baez (Selena: The Series), Kevin Carroll (Snowfall), Ian Foreman (Merry Wish-Mas) and Jacob Buster (Colony). Award-winning playwright, writer and producer Andrew Hinderaker (Away, PENNY DREADFUL), who wrote the pilot, will serve as showrunner and executive produce along with Seith Mann (HOMELAND, FreeRayshawn, Blindspotting), who directed the pilot and will also direct additional episodes.